Tube Racks
Abcam Salvinorin A (Divinorin A), kappa agonist, 5MG
MW 432.5 Da, Purity >98%. Potent κ agonist (Ki = 8-19 nM). Psychoactive and antinociceptive in vivo. Reported to be an allosteric modulator of μ opioid receptors.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Forskolin, Adenylyl cyclase activator, 50MG
MW 410.5 Da. Cell-permeable activator of adenylyl cyclase. Interacts directly with the catalytic subunit of the enzyme to increase intracellular cAMP levels. Positive inotropic, platelet antiaggregatory and antihypertensive actions in vivo. 3D Growth matrix component used in liver organoid generation.
The product is subject to the following: Abcam Restricted Use Statement
Azenta US Inc 1 PIECE RACK,48-FORMAT,10/CS
Rack, 48-format, 1 piece rack base, 10 racks per case, suitable for 48-format External Thread Tri-coded Tubes
Abcam Compound E, gamma;-secretase inhibitor, 1MG
MW 490.5 Da, Purity >99%. Cell-permeable, selective, non-competitive, potent γ-secretase inhibitor (IC₅₀ = 0.3 nM). Active in vitro and in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam CAY10574, Cdk9 kinase inhibitor, 10MG
MW 218.2 g/mol, Purity >95%. Potent, selective Cdk9 kinase inhibitor (IC₅₀ = 350 nM). Moderate ATP-competitive Cdk2-cyclin E inhibitor (IC₅₀ = 20 μM). Induces cell cycle arrest, decreasing S-phase. Shows antiproliferative effects (IC₅₀ values are 33, 49, 64 and 62 μM for MCF7, HOS, G361, and K562 cells respectively).
The product is subject to the following: Abcam Restricted Use Statement
Abcam CAY10602, SIRT1 Activator, 10MG
MW 418.4 Da, Purity >95%. SIRT1 Activator. Suppresses NF-κB-dependent induction of TNF-α by LPS (IC₇₀ = 60 μM, THP-1 cells). Upregulates PPARδ-mediated transcription in ECs.
The product is subject to the following: Abcam Restricted Use Statement
Abcam CAY10602, SIRT1 Activator, 50MG
MW 418.4 Da, Purity >95%. SIRT1 Activator. Suppresses NF-κB-dependent induction of TNF-α by LPS (IC₇₀ = 60 μM, THP-1 cells). Upregulates PPARδ-mediated transcription in ECs.
The product is subject to the following: Abcam Restricted Use Statement
Abcam NSC 663284 (DA3003-1), Cdc25 inhibitor, 5MG
MW 321.76 Da, Purity >98%. Potent, cell-permeable, irreversible non-selective Cdc25 inhibitor. Induces cell cycle arrest at both G1 and G2/M phase. Shows antiproliferative effects against tumor cell lines (IC₅₀ = 0.2-35 μM). Shows antitumor effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam CAY10574, Cdk9 kinase inhibitor, 1MG
MW 218.2 g/mol, Purity >95%. Potent, selective Cdk9 kinase inhibitor (IC₅₀ = 350 nM). Moderate ATP-competitive Cdk2-cyclin E inhibitor (IC₅₀ = 20 μM). Induces cell cycle arrest, decreasing S-phase. Shows antiproliferative effects (IC₅₀ values are 33, 49, 64 and 62 μM for MCF7, HOS, G361, and K562 cells respectively).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Alternariol monomethyl ether, antifungal phytoto x ic compound, 1MG
MW 272.25 Da, Purity >98%. Antifungal phytotoxic compound. Inhibits electron transport chain in chloroplasts. Possesses DNA strand-breaking activity. Inhibits topoisomerase IIα activity. Active in vitro. See similar compound
The product is subject to the following: Abcam Restricted Use Statement
Abcam MTEP, mGluR5 antagonist, 25MG
MW 200.26 Da, Purity >99%. Potent and selective mGluR5 antagonist. Acts as a negative allosteric modulator at mGluR5. Shows 5-fold more potent anxiolytic effects than MPEP (ab120008). Shows antidepressant and neuroprotective effects in vivo. Orally active. Blood-brain barrier permeable.
The product is subject to the following: Abcam Restricted Use Statement
Abcam MTEP hydrochloride (mM/ml), mGlu5 antagonist, 10MM_ML
MW 236.72 Da, Purity >99%. Brain penetrant, potent, selective and non-competitive mGlu5 receptor antagonist (IC50 = 5 nM in Ca2+-flux assay; Ki = 16 nM). In vivo anxiolytic, devoid of side effects seen with MPEP and benzodiazepines. Soluble in 1 ml water to give specified mM/ml concentration.
The product is subject to the following: Abcam Restricted Use Statement